PREDICTING LIVE BIRTH, PRETERM DELIVERY, AND LOW BIRTH WEIGHT IN INFANTS BORN FROM IN VITRO FERTILISATION: A PROSPECTIVE STUDY OF 144,018 TREATMENT CYCLES.

Predicting live birth, preterm delivery, and low birth weight in infants born from in vitro fertilisation: a prospective study of 144,018 treatment cycles.

BackgroundThe extent to which baseline couple characteristics affect the probability of live birth and adverse perinatal outcomes after assisted conception is unknown.Methods and findingsWe utilised the Human Fertilisation and Embryology Authority database to examine the predictors of live birth in all in vitro fertilisation (IVF) cycles undertaken

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Network-based clustering unveils interconnected landscapes of genomic and clinical features across myeloid malignancies

Abstract Myeloid malignancies exhibit considerable heterogeneity with overlapping clinical and genetic features among subtypes.We present a data-driven approach that integrates mutational features and clinical covariates at diagnosis within networks of their probabilistic relationships, enabling the discovery of patient subgroups.A key strength is

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Risk factors and outcomes for late presentation for HIV-positive persons in Europe: results from the Collaboration of Observational HIV Epidemiological Research Europe Study (COHERE).

BackgroundFew studies have monitored late presentation (LP) of HIV infection over the Tweed Gloves European continent, including Eastern Europe.Study objectives were to explore the impact of LP on AIDS and mortality.Methods and findingsLP was defined in Collaboration of Observational HIV Epidemiological Research Europe (COHERE) as HIV diagnosis wit

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